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 | Urticaria, the medical term for hives, is caused by the release of histamine into the skin by allergic cells such as mast cells. Chronic urticaria is often due to unknown causes or due to autoimmune disease. While antihistamines are the mainstay of treatment for chronic urticaria, many people find that there symptoms are not controlled with routine dosages of antihistamines. Xolair, an injectable medication for the treatment of asthma, targets IgE before it has the chance to bind to mast cells and cause the release of histamine into the skin. Xolair has been shown to reduce, and in some cases eliminate, symptoms in people with chronic hives. It will be interesting to see if Xolair is eventually approved for the treatment of chronic hives. |
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Xolair for the Treatment of Hives
Urticaria, the medical term for hives, is a condition that can affect up to one in five people at some point during their lifetime. The rash of urticaria is usually bumpy, red and itchy. The bumps can be the size of mosquito bites to coin-size or larger, and can group together into irregular shapes, which is called coalescing. The rash will tend to come and go within a few hours, moving from one place on the body to another.
| What is Xolair?
Xolair (omalizumab) is an injectable medication used to treat moderate to severe allergic asthma. It can be used in people 12 years and older who still have uncontrolled asthma despite typical asthma medications, such as inhaled steroids. Injections are given in the doctor’s office every 2 to 4 weeks, depending on a person’s weight and allergic antibody (IgE) level.
| All About Hives
Urticaria, commonly known as hives, is a disorder affecting up to 20% of the population at some point in their lives. The swelling that sometimes accompanies hives, called "angioedema," can lead to swelling of the face, hands and feet. Hives usually feel very itchy and burning (although angioedema is often painful) or cause a tingling sensation — and these symptoms often make people miserable.
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